We apply the Displacement Framework to multiple sclerosis (MS), formalizing intact myelinated conduction as S0_myelin. Each demyelinating lesion is a displacement event adding to total Phi. Remyelination is partial return. RRMS is cyclical displacement with shrinking return windows; SPMS is wrong-attractor lock-in through OPC exhaustion. DMTs are displacement-rate reducers, not restorers.
Fatigue is the metabolic surcharge of sustained Phi above zero. The EDSS scale is reinterpreted as a Phi_accumulated proxy.
Phronesis