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The Immunological Ground State: Tolerance, Inflammatory Displacement, and the Autoimmune Wrong Attractor

Rincón, D. · 2026 · Zenodo

This is the record, not the paper. The work itself is the deposit on Zenodo, under the DOI below. What follows is its abstract, as deposited.

We apply the Displacement Framework to the immune system. S0_immune is the tolerant, surveilling, non-inflammatory configuration. Acute infection is correct bounded displacement with resolution via Tregs, IL-10, and specialized pro-resolving mediators. Chronic inflammation is return failure. Autoimmunity is wrong-attractor capture — tolerance lost. Allergic disease is a Th2/IgE wrong attractor.

Immunodeficiency is insufficient displacement capacity. Vaccination is attractor pre-shaping that reduces lifetime displacement burden. The immune-gut axis is formalized as external attractor-depth regulation via microbiome-derived SCFAs and Foxp3 Treg induction. Eight formal propositions are derived.

displacement framework · immune system · autoimmunity · inflammation · tolerance · vaccination

Read the deposit on Zenodo →doi 10.5281/zenodo.20407875

nearby in the index

The Hormone-Blushing Correspondence: One Surface Signal, Multiple Internal Displacement States, and the Partial Honesty of Facial VasodilationThe Human Displacement Compact (DCH): A Formal Specification of Human Ground State, Displacement Dimensions, and Return PathsThe Mammal Displacement Compact (DCM): Ground State, Displacement, and Return Across the Class MammaliaThe Mathematical Foundations of Displacement Dynamics: Ground States, Attractor Geometry, and the Formal Structure of Return